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1 edition of System for estimation of mean active bone marrow dose found in the catalog.

System for estimation of mean active bone marrow dose

System for estimation of mean active bone marrow dose

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Published by U.S. Dept. of Health, Education, and Welfare, Public Health Service, Food and Drug Administration, Bureau of Radiological Health ; Govt. Print. Off. in Rockville, Md .
Written in English

    Subjects:
  • Bone Marrow -- radiation effects.,
  • Radiation -- Safety measures.,
  • Radiometry.

  • Edition Notes

    Statementby R.E. Ellis ... [et al.].
    SeriesDHEW publication -- no. (FDA) 76-8015
    ContributionsEllis, R. E., United States. Bureau of Radiological Health.
    The Physical Object
    Paginationviii, 50 p. :
    Number of Pages50
    ID Numbers
    Open LibraryOL18235207M

    -When cells of the lymphatic system are damaged the body loses some of its ability to combat infection. Because the number of platelets also decreases with loss of bone marrow function, the body loses a corresponding amount of it blood-clotting ability. This makes the body more susceptible to hemorrhage.   Hematopoiesis is the process of creating new blood cells from stem cells. It happens naturally in the body, starting when a human is still an : James Roland.

      A quantitative measure of bone marrow fat fraction is the Iterative Decomposition of Water and Fat with Echo Asymmetric and Least—Squares Estimation (IDEAL) imaging technique, which can be used to create parametric fat fraction maps, providing both quantitative and spatially resolved information on marrow composition ().Cited by: Indications for Bone Marrow Aspiration or Biopsy. Bone marrow evaluation provides important diagnostic information on the hematopoietic status of an animal; it is typically performed to evaluate hematopoiesis and to detect evidence of neoplastic or infectious disease ().The complete blood cell count (CBC) is the most common method used to evaluate the hematopoietic system, but a more.

    the lymphatic tissues secondarily. In toto, the bone marrow constitutes an organ that rivals the liver in weight and in humans is estimated to account for 4% to 5% of body weight. Types Bone marrow is an extremely cellular connective tissue that fills the medullary cavities of bone. On gross inspection, it may have a red or yellow color. Bone marrow is a semi-solid tissue found within the spongy or cancellous portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production or hematopoiesis. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the : D


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System for estimation of mean active bone marrow dose Download PDF EPUB FB2

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Rockville, Md.: U.S. Dept. of Health, Education, and Welfare, Public Health Service, Food and Drug Administration, Bureau of Radiological Health ; Govt. Print. Off., (OCoLC) Online version: System for estimation of mean active bone marrow dose. In order to evaluate the average bone marrow dose, therefore, it is necessary to know how the radiation is distributed in relation to the active marrow.

For proper determination of radiation exposure, a system of monitoring which yields information about both total exposure and exposure distribution is by: 5. Dosimetry estimation is mandatory to avoid haematological toxicity resulting from absorbed dose delivered to bone marrow [2].

Bone marrow is the most radiosensitive tissue in the body and it is commonly considered the critical organ for radionuclide therapy. This tissue is spread throughout the skeleton, within the cavities of the bones.

Active bone marrow absorbed doses were estimated for workers as part of a nested case-control study of multiple myeloma mortality at the Oak Ridge Gaseous Diffusion Plant (K). Uranium urinalysis results obtained by fluorometric and gross alpha measurements were available for about 20% of the study subjects.

Bone marrow is a nutrient-rich spongy tissue located mainly in the hollow portions of marrow: red marrow and yellow marrow. Yellow marrow has a much higher amount of fat cells than red marrow. Both types of marrow contain blood vessels. Personalized estimation of dose to red bone marrow and the associated leukaemia risk attributable to pelvic kilo-voltage cone beam computed tomography scans in image-guided radiotherapy.

Yibao Zhang 1, Yulong Yan 2, Ravinder Nath 3, Shanglian Bao 1 and Jun Deng 3,4. Published 2 July • Institute of Physics and Engineering in Medicine. Distribution of Bone Marrow. (London) - PMID — "The distribution of active bone marrow in the adult." Ellis RE et al. Phys Med Biol.

Jan; By weighing cadaveric bones. Results: Mean total bone marrow doses ranged from to Gy in the phantom study. Approximately 99% of the mean dose to the total bone marrow comes from the dose to bone marrow located in the pelvic bones and lumbar by:   The white spaces are fat cells that have washed out during processing; the cells in between the fat cells are hematopoietic precursors.

The ratio of cells to fat is called the “cellularity.” The marrow above is approximately % cellular. You need to know the age of the patient to estimate whether the cellularity is normal. [A method for estimation of active bone marrow dose from x-ray radiography (author's transl)].Author: Takaku Y.

There are two types of bone marrow: red marrow and yellow marrow. Yellow marrow has a much higher amount of fat cells than red marrow. Both types of marrow contain blood vessels.

Stem Cells The bone marrow works like a ‘factory’ that produces all of the cells that are found in the bone marrow and in the peripheral blood stream. activity) to the mean absorbed dose to the bone marrow, D BM: activity in the bone marrow itself, activity in bone, and activity in major tissues and the remainder of the body.

Furthermore, the macroscopic self-absorbed dose to the bone marrow can on a microscopic scale be further divided into the contributions from activity in bone marrow cells.

Existing data on bone marrow distribution have been determined from the weight and visual appearance of the marrow in cadavers. {sup 18}F-fluoro-L-deoxythymidine concentrates in bone marrow, and we used its intensity on positron emission tomography imaging to quantify the location of the proliferating bone marrow.

For example, values of absorbed fraction for the self-dose to active bone marrow in the ribs, cervical vertebra, and parietal bone are, and for 6-MeV alpha-particles and are Dose distributions in active bone marrow were measured in a tissue-equivalent human phantom.

Dose equivalents for the partial-body exposure conditions were determined by applying the phantom marrow dose distributions to a model for nonuniform exposure based on stem-cell dose-survival by: 9.

Background. The study aims to develop and validate an automatic delineation method for estimating red bone marrow (RM) activity concentration and absorbed dose in 89 Zr positron emission tomography/computed tomography (PET/CT) studies.

Five patients with advanced colorectal cancer received ± MBq [89 Zr] cetuximab within 2 h after administration of a therapeutic dose of Cited by: 1. This atlas has potential utility for estimating the distribution of active marrow in adult cancer patients to guide radiation therapy planning.

However, because of interindividual variation it should be used with caution when radiation therapy risks ablating large proportions of active marrow; in such cases, individual FLT-PET scans may be Cited by:   Yellow bone marrow is involved in the storage of fats.

The fats in yellow bone marrow are stored in cells called adipocytes. This fat can be used as an energy source as needed. Citation: Mansouritorghabeh H, Ghasemi A () The Current Role of Bone Marrow Transplantation in the Treatment of Hemophilia A.

J Hematol Thrombo Dis 2: doi: /. Only active bone marrow dose from photofluorographic chest and routine lumbar spine x rays were included. Bone marrow dose assigned for a single exposure ranged from to mGy.

Mean and median cumulative bone marrow doses for each of the five sites from work-related x-ray examinations ranged from to 14 mGy and to mGy, respectively.Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often called trephine biopsy) and bone marrow marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, lymphoma, anemia, and bone marrow produces the cellular elements of the blood, MeSH: D  Adult bone marrow contains numerous adipocytes, whose numbers correlate inversely with the haematopoietic activity.

Disorders of excess haematopoiesis, such Cited by: